METHOD FOR THE PREPARATION OF PALLADIUM(I) TRI-TERT-BUTYLPHOSPHINE BROMIDE DIMER

摘要

The invention provides a new method for the preparation of the dimeric Pd(l) tri-tert.-butylphosphine bromide complex, characterized by the chemical formula [Pd(-Br)(PtBu3)]2. The method is based on a comproportionation reaction in which a Pd(ll) compound (PdBr2) is reacted with a Pd(0) compound (Pd(PtBu3)2) in organic solvents to yield the [Pd(-Br)(PtBu3)]2 compound having the Pd atoms in the formal oxidation state +1. Unreacted PdBr2 may be reused in the process. The method is straightforward and applicable for industrial scale production and provides high product yields. Further, a new process for the isomerization of allyl ethers of the general type R1C(O)OCH(R2)C(R3)CH2 employing the compound Pd-Br)(PtBu3)]2 as a catalyst is disclosed.