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METHOD FOR ESTIMATING GLOMERULAR FILTRATION RATE FROM MEASUREMENT VALUE OF MEGALIN IN URINE

机译:从尿中麦加林的测定值估算肾小球滤过率的方法

摘要

The object of the present invention is to provide a method for estimating the glomerular renal function in a convenient and non-invasive manner. As a result of intensive studies to achieve the above object, the present inventors found that there is a high correlation between the urinary megalin excretion rate and the estimated glomerular filtration rate (eGFR) in renal disease patients, and the glomerular filtration rate (GFR) can be estimated with high probability in a non-invasive manner by measuring the megalin level in the urine. This has led to the completion of the present invention.
机译:本发明的目的是提供一种以方便且非侵入性的方式估计肾小球肾功能的方法。作为实现上述目的的深入研究的结果,本发明人发现,肾脏疾病患者中的尿巨蛋白排泄率与估计的肾小球滤过率(eGFR)和肾小球滤过率(GFR)之间具有高度相关性。可以通过测量尿液中的巨蛋白水平以非侵入性方式高估概率。这导致了本发明的完成。

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