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VACCINE COMPOSITIONS AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME AND PORCINE CIRCOVIRUS ASSOCIATED DISEASES
VACCINE COMPOSITIONS AGAINST PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME AND PORCINE CIRCOVIRUS ASSOCIATED DISEASES
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机译:抵抗猪繁殖与呼吸综合征和猪循环病毒相关疾病的疫苗成分
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摘要
A fusion protein comprising an antigen-presenting cell (APC)-binding domain or a CD91 receptor-binding domain, a translocation peptide, a fusion antigen, an endoplasmic reticulum retention sequence, and optionally a nuclear export signal is disclosed. The fusion antigen comprises a porcine reproductive and respiratory syndrome virus (PRRSV) ORF7 antigen, a PRRSV ORF1b antigen, a PRRSV ORF6 antigen, and a PRRSV ORF5 antigen. The fusion protein is useful for inducing antigen-specific cell-mediated and humoral responses.
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