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HNRNP A2* PROTEIN, NUCLEIC ACID FOR CODING PROTEIN AND USE THEREOF
HNRNP A2* PROTEIN, NUCLEIC ACID FOR CODING PROTEIN AND USE THEREOF
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机译:HNRNP A2 *蛋白质,用于编码蛋白质的核酸及其用途
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摘要
The present invention provides an hnRNP A2* protein, nucleic acid for coding the protein and a use thereof. The protein contains a protein, a protein segment or a protein analog or derivative having an amino acid sequence shown as SEQ ID NO. 1. The hnRNP A2* protein can actively unloosen telomere G-quadruplexes, bind the minimum binding site at the 3' tail end of telomere, expose five nucleotide tails which can be matched with a telomere enzyme RNA template and promote the extension of telomere under the effect of telomere enzyme, thereby maintaining the cell division potential.
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机译:本发明提供了hnRNP A2 *蛋白,用于编码该蛋白的核酸及其用途。该蛋白质包含具有如SEQ ID NO.1所示的氨基酸序列的蛋白质,蛋白质区段或蛋白质类似物或衍生物。 1. hnRNP A2 *蛋白可主动释放端粒G-四链体,结合端粒3'尾端的最小结合位点,暴露5个可与端粒酶RNA模板匹配的核苷酸尾巴,并在以下条件下促进端粒的延伸端粒酶的作用,从而保持细胞分裂的潜力。
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