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MICROFLUIDIC ARRAY SUPPORTING A LIPID BILAYER ASSEMBLY

机译:支持脂质双层组件的微流控阵列

摘要

A microfluidic array supporting a lipid bilayer assembly on which membrane proteins can be assembled is described. The array is formed from a hydrophilic polymeric substrate or metal substrate comprising a planar surface with a plurality of individual spherical depressions formed therein. Each of the depressions are configured to have a diameter greater than 1 μm and containing an aqueous solution. Across each of the depressions is provided a lipid layer. Each of the plurality of individual depressions comprise arcuate side walls extending downwardly into the substrate from the planar surface.
机译:描述了支持脂质双层组件的微流体阵列,膜蛋白可以在脂质双层组件上组装。该阵列由亲水性聚合物基底或金属基底形成,该亲水性聚合物基底或金属基底包括在其中形成有多个单独的球形凹陷的平面表面。每个凹陷被配置为具有大于1μm的直径并且包含水溶液。跨每个凹陷提供脂质层。多个单独的凹陷中的每一个包括从平坦表面向下延伸到基板中的弧形侧壁。

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