MULTIPLEX BEAD BASED ASSAY FOR QUANTIFICATION OF MULTIPLE TYPES OF CARRIER PROTEIN IN A MULTIVALENT CONJUGATE VACCINE COMPOSITION

摘要

The present disclosure relates to a bead based competitive inhibition assay for estimation of individual concentration of carrier proteins in a multivalent polysaccharide protein (Ps-Pr) conjugate vaccine composition, wherein said composition comprises of atleast 2 different types of carrier protein. The instant disclosure helps to overcome the limitations of physico-chemical techniques for protein quantification and other immunological assay like ELISA.