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COMBINED MEDICATION EFFICACY PROCESSING METHOD AND APPARATUS
COMBINED MEDICATION EFFICACY PROCESSING METHOD AND APPARATUS
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机译:联合用药效率处理方法和装置
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摘要
Provided are a processing method and a processing apparatus for efficacy of a combined drug. The processing method includes: obtaining a dose-effect curve band of an expected additive effect of the combined drug (S202); obtaining an actual dose-effect relationship curve formed by an actual effect value of the combined drug with a dose change of one target component drug in the combined drug (S204); comparing a positional relationship between the actual dose-effect relationship curve and the dose-effect curve band (S206); and outputting the efficacy of the combined drug as a synergistic effect when the actual dose-effect relationship curve is located above the dose-effect curve band, outputting the efficacy of the combined drug as an antagonistic effect when the actual dose-effect relationship curve is located below the dose-effect curve band, and outputting the efficacy of the combined drug as an additive effect when the actual dose-effect relationship curve is located within a range of the dose-effect curve band (S208). The processing method not only solves the problem that the efficacy cannot be accurately detected when multiple drugs are combined in the conventional art, but also can be widely applied in research and development as well as toxicology research of a compound drug, efficacy and safety evaluation of the combined drug and environment evaluation.
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