ACTIVIN-ActRII ANTAGONISTS AND USES FOR TREATING BONE DISORDERS AND OTHER DISORDERS

摘要

PROBLEM TO BE SOLVED: To provide methods for treatment of bone disorders that are associated with kidney disease, such as chronic kidney disease-mineral and bone disorder (CKD-MBD), low-metabolic turnover bone disorders and vascular calcification.;SOLUTION: The methods comprise administration of an activin-ActRIIA inhibitor to a subject in need of the treatment. The activin-ActRIIA inhibitor is a polypeptide comprising a specific amino acid sequence.;SELECTED DRAWING: Figure 1;COPYRIGHT: (C)2019,JPO&INPIT