首页> 外国专利> DETECTION METHOD FOR PRESENCE OF DISEASE INVOLVING GLO1 EXPRESSION, MARKER USED IN THE DETECTION METHOD, GLO1 ENZYME ACTIVITY IMPROVER, AND GLO1 ENZYME ACTIVITY REDUCING AGENT

DETECTION METHOD FOR PRESENCE OF DISEASE INVOLVING GLO1 EXPRESSION, MARKER USED IN THE DETECTION METHOD, GLO1 ENZYME ACTIVITY IMPROVER, AND GLO1 ENZYME ACTIVITY REDUCING AGENT

机译:涉及GLO1表达的疾病的检测方法,检测方法中使用的标记,GLO1酶活性的赋予和GLO1酶活性的降低剂

摘要

PROBLEM TO BE SOLVED: To provide a method for detecting a disease involving the expression of GLO1 by analyzing details of the expression of GLO1, a marker used in the detection method, a GLO1 enzyme activity improver, and a GLO1 enzyme activity reducing agent.;SOLUTION: According to the present invention, there are provided a method, etc., based on the finding that there are 8 different gene polymorphisms present in the thymine repeat sequence within the GLO1 promoter region, a gene polymorphism with 15 thymines is involved in the enhancement of GLO1 transcriptional activity, and the proportion of the gene polymorphism correlates with a disease involving the expression of GLO1.;SELECTED DRAWING: None;COPYRIGHT: (C)2018,JPO&INPIT
机译:解决的问题:提供一种通过分析GLO1表达的细节,检测方法中使用的标记,GLO1酶活性促进剂和GLO1酶活性降低剂来检测涉及GLO1表达的疾病的方法。解决方案:根据本发明,提供了一种方法等,基于发现在GLO1启动子区域内的胸腺嘧啶重复序列中存在8种不同的基因多态性,而该基因涉及15种胸腺嘧啶的基因多态性。 GLO1转录活性的增强,以及基因多态性的比例与涉及GLO1表达的疾病有关。;部分提要:无;版权:(C)2018,JPO&INPIT

著录项

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号