Evaluation of NFkB cell signaling pathway activity using mathematical modeling of target gene expression

摘要

The present invention relates to a method comprising estimating the activity of the NFkB cell signaling pathway based at least on the expression level of 6 or more target genes of the NFkB cell signaling pathway measured in the sample. The invention further relates to a device comprising a digital processor configured to implement such a method, a non-transitory storage medium storing instructions executable by the digital processing device, for implementing such a method, And a computer program containing program code means for causing the digital processing device to perform such a method. The present invention further relates to a kit for measuring expression level.