Inhibitors of mutant isocitrate dehydrogenase IDH1 R132H

摘要

The present invention relates to (2E) -but-2-enedioic acid-3- (2-{[4- (trifluoromethoxy) phenyl] amino} -1-[(1R, 5R) -3,3,5- Trimethylcyclohexyl] -1H-benzimidazol-5-yl) propanoic acid (1: 4) adduct, a process for preparing the adduct, a pharmaceutical composition comprising the adduct and also a medicament for the treatment of disease It relates to the use of this adduct for preparation.