HYPROMELLOSE PHTHALIC ACID ESTER AND MANUFACTURING METHOD OF HYPROMELLOSE PHTHALIC ACID ESTER

摘要

PROBLEM TO BE SOLVED: To provide a manufacturing method of HPMCP capable of reducing average particle diameter of HPMCP particles to a desired range without passing a pulverization process.SOLUTION: There is provided a manufacturing method of hypromellose phthalic acid ester at least including an esterification process for reacting hypromellose and an esterification agent in the presence of a catalyst to obtain a reaction solution, a deposition process for mixing the reaction solution and water to obtain a hypromellose phthalic acid ester suspension by deposition of crude hypromellose phthalic acid ester, a dehydrating process for dehydrating the hypromellose phthalic acid ester suspension by using a centrifugal decanting machine to obtain dehydrated hypromellose phthalic acid ester, and a drying process for drying the hypromellose phthalic acid ester.SELECTED DRAWING: None