Method for treating alopecia areata using a gene regulatory approach

摘要

The present invention relates to methods and compositions for the treatment of alopecia areata. In some aspects, the present invention relates to a hapten for use in the treatment of alopecia areata. In other aspects, the present invention relates to RNAi constructs with improved tissue / cell uptake properties and the use of these compounds in the treatment of alopecia areata. In another aspect, the invention relates to a composition comprising a hapten formulated as a gel or ointment.