Interference detection and deconvolution of peak of interest

摘要

Intensity measurements are generated for one or more compounds from the mixture. Intensity traces are calculated for a range of measured dimensions that are known to contain product ions of known compounds. An intensity value is selected for the intensity trace. For each measurement point over the range, each intensity trace is scaled to have a minimum intensity, a common component profile is calculated as a summary of the minimum intensity of the scaled intensity trace over the range, and the score is common Calculated for component profiles. Optimally minimize the distance between the maximum value of the common component profile and each measurement point, maximize the area of the common component profile, and minimize the area of subtraction of the common component profile from the scaled intensity trace The optimal common component profile having a score compared to the scores of the other profiles is selected.