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Use of α- (8-quinolinyloxy) monosubstituted phthalocyanine zinc for treating psoriasis

机译:α-(8-喹啉基氧基)单取代的酞菁锌在治疗牛皮癣中的用途

摘要

The present invention relates to the use of α- (8-quinolinyloxy) monosubstituted zinc phthalocyanine for treating psoriasis. Adopt photodynamic therapy and apply to each type of psoriasis. The photosensitizer has a laser wavelength of 670 nm used to treat psoriasis, has high photosensitivity, fast photobleaching, requires a short light-reducing time, and is irradiated with ultraviolet rays in photodynamic therapy. Avoided toxic side effects due to use. For the use of α- (8-quinolinyloxy) mono-substituted phthalocyanine zinc to treat psoriasis, the formulations used include solutions, creams, nanomicelles, microparticles and the like. The dosing method may be systemic dosing or local dosing. In cell and animal models, it was verified that psoriasis can be performed by photodynamic therapy, and the ideal effect was obtained.
机译:本发明涉及α-(8-喹啉基氧基)单取代的酞菁锌在治疗牛皮癣中的用途。采用光动力疗法并适用于各种类型的牛皮癣。该光敏剂具有用于治疗牛皮癣的670nm的激光波长,具有高的光敏性,快速的光漂白,需要短的减光时间并且在光动力疗法中被紫外线照射。避免因使用而产生毒副作用。为了将α-(8-喹啉基氧基)单取代的酞菁锌用于治疗牛皮癣,所用的制剂包括溶液,乳膏,纳米胶束,微粒等。给药方法可以是全身给药或局部给药。在细胞和动物模型中,已证实可以通过光动力疗法治疗牛皮癣,并获得了理想的效果。

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