Separation method, detection method, signal measurement method, disease determination method, drug efficacy evaluation method, kit, liquid composition, and specimen diluent

摘要

To provide a method capable of reducing non-specific adsorption to a solid phase carrier and selectively and efficiently separating vesicles having a lipid bilayer membrane. A biological sample containing a vesicle having a lipid bilayer membrane is contacted with a solid phase carrier to which a ligand that recognizes a surface antigen present on the surface of the vesicle is bound, and the vesicle and the solid phase carrier are combined. A complex forming step for forming a body and a washing step for washing the complex, and performing at least one of the complex forming step and the washing step in an environment having a salt concentration of 0.15 to 2M. A method for separating a vesicle having a lipid bilayer, which is characterized.