首页> 外国专利> A compound for immobilizing a lipid membrane-containing substance, a substrate modified with the compound, a method for patterning a lipid membrane-containing substance on the substrate, and a method for isolating a lipid membrane-containing substance on the substrate

A compound for immobilizing a lipid membrane-containing substance, a substrate modified with the compound, a method for patterning a lipid membrane-containing substance on the substrate, and a method for isolating a lipid membrane-containing substance on the substrate

机译:用于固定含脂质膜物质的化合物,用该化合物改性的基质,在基质上构图含脂质膜物质的方法以及在基质上分离含脂质膜物质的方法

摘要

The present invention relates to a compound of formula (I), wherein A1Is a lipid membrane binding group that binds to the lipid membrane in the lipid membrane-containing material, and A2Is a lipid membrane binding inhibiting group which inhibits the binding of the lipid membrane binding group to the lipid membrane, and A3Is a photoreactive group and A4Is a hydrophilic group, and A5Is a reactive group to a substrate to be modified, and A6Is a scaffold site having at least three binding hands, and L1And L2Is a linker, k1And k2Are each independently 0 or 1], the binding inhibition due to the lipid membrane-bound inhibiting group is eliminated by the photoreaction, and the lipid membrane binding group can bind to the lipid membrane A substrate modified with the compound, a method for patterning a lipid film-containing substance on the substrate, and a method for isolating a lipid film-containing substance on the substrate.
机译:本发明涉及式(I)的化合物,其中A 1 是与含脂质膜的材料中的脂质膜结合的脂质膜结合基,A 2 < / Sup>是脂质膜结合抑制基团,其抑制脂质膜结合基团与脂质膜的结合,A 3 是光反应性基团,而A 4 Is是一个亲水基团,而A 5 是对要修饰的底物的反应基团,而A 6 是一个具有至少三个结合手的支架位点,而L 1 和L 2 是一个连接子,k 1 和k 2 分别是0或1],结合抑制由于通过光反应消除了与脂质膜结合的抑制基团,并且脂质膜结合基团可以结合到用该化合物修饰的脂质膜A底物,在底物上构图含脂质膜的物质的方法和脂质f的分离方法基材上含有ilm的物质。

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