Medicament for treating or preventing a disorder caused by TGF-β, including a caspase inhibitor, and application thereof

摘要

Provided is a medicament or method for treating or preventing a corneal endothelial symptom, disorder or disease resulting from at least one of transforming growth factor-β (TGF-β) signal and mitochondrial abnormality in corneal endothelial cells. The present invention provides a medicament for treating or preventing a corneal endothelial symptom, disorder or disease caused by at least one of TGF-β signal and mitochondrial abnormality in corneal endothelial cells, comprising a caspase inhibitor. In a preferred embodiment, the corneal endothelium symptom, disorder or disease is Fuchs corneal endothelial dystrophy.