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One dimensional photonic crystals for enhanced fluorescence based sensing, imaging and assays
One dimensional photonic crystals for enhanced fluorescence based sensing, imaging and assays
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机译:一维光子晶体,用于增强基于荧光的传感,成像和测定
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摘要
Techniques for enhanced fluorescence include a functionalized substrate for a target optical frequency comprising a one dimensional photonic crystal that is functionalized with a bioactive target molecule that has an affinity for a particular analytic. The one dimensional photonic crystal includes a plurality of dielectric layers including a plurality of high index of refraction layers alternating with a plurality of low index of refraction layers. The thickness of each layer is within a factor of four of a wavelength of the optical frequency in the layer. For emissions from a fluorophore bound to the target molecule and excited by incident light, there is an emission intensity maximum centered at an angle independent of the direction of the incident light.
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