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AIPA, OMPA, and ASP14 in vaccine compositions and diagnostic targets for anaplasma phagocytophilum infection
AIPA, OMPA, and ASP14 in vaccine compositions and diagnostic targets for anaplasma phagocytophilum infection
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机译:疫苗组合物中的AIPA,OMPA和ASP14和吞噬嗜血细胞无性感染的诊断目标
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摘要
Anaplasma phagocytophilum surface protein AipA and/or fragments thereof which comprise an invasin domain are used in compositions suitable to elicit an immune response to treat or prevent infections caused by tick-born bacteria of the Anaplasmatacaea family. AipA proteins and protein fragments or antibodies directed to AipA proteins and protein fragments are also used in diagnostic assays to detect exposure to and/or infection with Anaplasmatacaea. AipA and/or fragments thereof are also used for these purposes in combination with one or both of Asp14 and OmpA proteins and/or fragments thereof which comprise an invasin domain. Homologs of these proteins are also used in the compositions and assays.
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