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MTAB-TA-Coated gold nanorods and method of fabrication

机译:MTAB-TA涂层的金纳米棒及其制造方法

摘要

11-mercaptoundecyl trimethylammonium bromide gold nanorod (MTAB-GNR) coated with tannic acid (TA), useful for biological cellular imaging. A method of synthesizing tannic acid-coated 11-mercaptoundecyl trimethylammonium bromide gold nanorods (MTAB-TA GNRs) comprising presenting 11-mercaptoundecyl trimethylammonium bromide gold nanorods (MTAB-GNRs) in solution; functionalizing the MTAB-GNRs with tannic acid (TA) added to the MTAB-GNRs, the tannic acid configured to form a coating around the MTAB-GNRs forming MTAB-TA GNRs. The functionalizing step may further comprise adding a sodium chloride solution to the MTAB-TA GNR solution, and/or adding a MOPS buffer to the solution of tannic acid with MTAB-GNRs, and the tannic acid MTAB-GNR solution may be vortexed after each step. The MTAB-TA GNR solution may be centrifuged to separate the MTAB-TA GNRs from residual tannic acid and supernatant, and sterile water may be added to the MTAB-TA GNR solution and centrifuging performed to remove residual tannic acid from the MTAB-TA GNRs.
机译:单宁酸(TA)包覆的11-巯基三甲基溴化甲基溴化铵金纳米棒(MTAB-GNR),可用于生物细胞成像。一种合成鞣酸涂层的11-巯基三甲基溴化铵金纳米棒(MTAB-TA GNRs)的方法,该方法包括将11-巯基三甲基溴化铵金纳米棒(MTAB-GNRs)呈递到溶液中。用添加到MTAB-GNR中的单宁酸(TA)对MTAB-GNR进行功能化,将单宁酸配置为在MTAB-GNR周围形成涂层,从而形成MTAB-TA GNR。官能化步骤可以进一步包括将氯化钠溶液添加到MTAB-TA GNR溶液中,和/或将MOPS缓冲液添加到具有MTAB-GNR的单宁酸溶液中,并且在每次之后将单宁酸MTAB-GNR溶液涡旋。步。可以将MTAB-TA GNR溶液离心以从残留单宁酸和上清液中分离出MTAB-TA GNRs,可以将无菌水添加到MTAB-TA GNR溶液中并进行离心以从MTAB-TA GNRs中除去残留的单宁酸。

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