Spinal Cord Devices and Methods for Promoting Axonal Regeneration

摘要

A spinal cord device comprises a body formed of a biocompatible, biodegradable matrix and includes a proximal cranial surface and a distal caudal surface for connection to two ends of an injured spinal cord after removal of an injured section. The body has two sets of through channels A, B, C, D, E and F with openings in the cranial surface and the caudal surface for connection of descending motor pathways from cranial white to caudal gray matter and ascending sensory pathways from caudal white to cranial gray matter of the two spinal cord ends. The device has a transversal diameter (D_t) within a range of from 9 to 13 mm, an anteroposterior diameter (D_a) and a length (L), and the ratio anteroposterior diameter/transverse diameter (RAPT) is in a range of from 0.5 to 1.0. Kits employ a plurality of such devices.