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Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers

机译：联合免疫疗法和放射疗法治疗Her-2阳性癌症

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摘要

This invention provides methods for inducing an immune response against a Her-2/neu antigen-expressing tumor and for treating the same and vaccinating against the same in human and canine subjects using a combination of radiation therapy and a recombinant attenuated Listeria strain vaccine.

机译：本发明提供了使用放射疗法和重组减毒的利斯特氏菌的组合在人和犬科动物中诱导针对表达Her-2 / neu抗原的肿瘤的免疫应答并对其进行治疗并对其进行疫苗接种的方法。 / I>毒株疫苗。 展开▼

著录项

公开/公告号US10016617B2

专利类型

公开/公告日2018-07-10

原文格式PDF

申请/专利权人 THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;
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申请/专利号US201514669629

发明设计人 NICOLA MASON;YVONNE PATERSON;
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申请日2015-03-26

分类号A61N5/10;A61K35/74;A61K38/19;A61K39;

国家 US

入库时间 2022-08-21 13:04:09

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