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Methods for Treating Severe Atopic Dermatitis by Administering an IL-4R Inhibitor

机译:通过使用IL-4R抑制剂治疗重症特应性皮炎的方法

摘要

The present invention provides methods for treating moderate-to-severe or severe atopic dermatitis (AD). The methods of the present invention comprise administering to a subject in need thereof one or more doses of an interleukin-4 receptor (IL-4R) inhibitor such as an anti-IL-4R antibody. In certain embodiments, the methods of the present invention are used to treat severe AD in a patient whose disease is not controlled with systemic therapy (e.g., cyclosporine A) or when such therapy is inadvisable.
机译:本发明提供了用于治疗中度至重度或重度的特应性皮炎(AD)的方法。本发明的方法包括向有需要的受试者施用一剂或多剂白介素-4受体(IL-4R)抑制剂,例如抗IL-4R抗体。在某些实施方案中,本发明的方法用于在其疾病不能通过全身疗法(例如环孢霉素A)控制或在这种疗法不可取的患者中治疗重度AD。

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