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METHODS AND SYSTEMS FOR DETERMINING RISK OF A PREGNANCY COMPLICATION OCCURRING

机译:确定妊娠并发症发生风险的方法和系统

摘要

The present disclosure relates to methods and systems for determining the risk of a complication of pregnancy occurring. Certain embodiments of the present disclosure provide a method of determining the risk of a complication of pregnancy occurring in a subject, the pregnancy arising in the subject from a conception from a maternal donor and a paternal donor. The method comprises receiving initial information comprising (i) initial genetic information and/or (ii) initial clinical information and/or (iii) initial lifestyle information, the initial information being from the subject and/or the maternal donor and/or the paternal donor; processing the initial information to classify the risk of a complication of pregnancy occurring in the subject as low risk or increased risk; for the subject having said increased risk, receiving further information, the further information comprising (i) further genetic information and/or (ii) further clinical information and/or (iii) further lifestyle information from the subject and/or the maternal donor and/or the paternal donor; processing the further information to classify the risk in the subject having said increased risk as moderate risk or high risk, thereby determining the risk of a complication of pregnancy occurring in the subject.
机译:本公开涉及用于确定发生妊娠并发症的风险的方法和系统。本公开的某些实施方案提供了一种确定受试者中发生妊娠并发症的风险的方法,该妊娠在受试者中是由于来自母体供体和父体供体的受孕而引起的。该方法包括接收初始信息,该初始信息包括(i)初始遗传信息和/或(ii)初始临床信息和/或(iii)初始生活方式信息,该初始信息来自受试者和/或母体供体和/或父体。捐赠者;处理初始信息以将受试者发生妊娠并发症的风险分类为低风险或高风险;对于具有所述增加的风险的受试者,接受进一步的信息,所述进一步的信息包括(i)进一步的遗传信息和/或(ii)进一步的临床信息和/或(iii)来自受试者和/或母体供体的进一步的生活方式信息,以及/或父亲的捐助者;处理进一步的信息以将具有所述增加的风险的受试者的风险分类为中度风险或高风险,从而确定受试者中发生妊娠并发症的风险。

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