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METHOD FOR PREDICTING A DRUG RESPONSE BASED ON THE ATTRACTOR DYNAMICS OF THE NETWORK OF A CANCER-CELL AND DEVICE FOR THE SAME

机译:基于癌症细胞和设备网络的吸引子动力学的药物反应预测方法

摘要

A drug efficiency calculation method comprises generating information regarding a perturbation state transition diagram which is a state transition diagram of a specific perturbation network generated by applying a perturbation corresponding to a specific drug to a specific network generated by mapping the gene mutation information of a cancer-cell to a nominal network, and calculating a score regarding the efficiency of the drug on the basis of the size of one or more basins of the perturbation state transition diagram.
机译:一种药物效率计算方法,包括生成关于扰动状态转变图的信息,该扰动状态转变图是通过将对应于特定药物的扰动应用于通过映射癌症的基因突变信息而生成的特定网络而生成的特定扰动网络的状态转变图。单元到标称网络,并基于扰动状态转换图的一个或多个盆的大小,计算有关药物效率的分数。

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