首页> 外国专利> COMPOSITION COMPRISING CREPIDIASTRUM DENTICULATUM EXTRACT FOR PREVENTING OR TREATING ISCHEMIA-REPERFUSION INJURY AND USE THEREOF

COMPOSITION COMPRISING CREPIDIASTRUM DENTICULATUM EXTRACT FOR PREVENTING OR TREATING ISCHEMIA-REPERFUSION INJURY AND USE THEREOF

机译：预防或治疗局部缺血再灌注损伤的包含脑室纹状体提取物的组合物及其用途

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摘要

Provided are a pharmaceutical composition including a Crepidiastrum denticulatum extract as an active ingredient; and a method for preventing or treating ischemia-reperfusion injury in a subject by using a food composition or the pharmaceutical composition.

机译：提供了一种药物组合物，该药物组合物包含齿兰假单胞菌提取物作为有效成分;通过使用食物组合物或药物组合物预防或治疗受试者的局部缺血-再灌注损伤的方法。 展开▼

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公开/公告号US2018085414A1

专利类型

公开/公告日2018-03-29

原文格式PDF

申请/专利权人 KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY;UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION;
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申请/专利号US201715717337

发明设计人 CHU WON NHO;HAK CHEOL KWON;JI-HYE YOO;JAEYOUNG KWON;JIN SOO PARK;HYUK-JAI JANG;SEONG-SU KIM;CHEON SOO PARK;HWA-MI LEE;HEE JU LEE;
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申请日2017-09-27

分类号A61K36/28;A23L33/105;A23L33;

国家 US

入库时间 2022-08-21 13:02:23

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2. 用于预防或治疗呼吸道炎症的包含荔枝草和红参的组合草药提取物作为活性成分的组合物及其用途 [P] . 中国专利： CN110621326A . 2019-12-27

3. COMPOSITION COMPRISING CREPIDIASTRUM DENTICULATUM EXTRACT FOR PREVENTING OR TREATING ISCHEMIA-REPERFUSION INJURY AND USE THEREOF [P] . 美国专利： US2019381122A1 . 2019-12-19

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1. Experimental Study on the Protection of Agrimony Extracts from Different Extracting Methods against Cerebral Ischemia-Reperfusion Injury [J] . Huiyuan Zhu, Yulong Bie, Jiang Wang, 中国医学科学杂志（英文版） . 2017,第004期

2. Pretreatment with scutellaria baicalensis stem-leaf total flavonoid prevents cerebral ischemia-reperfusion injury [J] . Shumin Zhao, Wei Kong, Shufeng Zhang, 中国神经再生研究（英文版） . 2013,第034期

3. Crepidiastrum denticulatum Extract Ameliorates Kidney Ischemia-Reperfusion Injury in Mice [J] . J.S. Kim, H.J. Jang, E.K. Jeong, Transplantation Proceedings . 2018,第4期

4. COMPOSITION COMPRISING AN EXTRACT OF HARDY KIWI FOR PREVENTING OR TREATING BALDNESS DISORDERS OR SEBORRHEIC SKIN DISORDERS [J] . Soap Perfumery and Cosmetics group Soap, Perfumery and Cosmetics . 2014,第12期

5. Patent Issued for Composition Comprising an Extract of Hardy Kiwi for Preventing Or Treating Baldness Disorders Or Seborrheic Skin Disorders [J] . Journal of Engineering . 2013,第13期

6. Preventing Injury and Fatalities-Applying a Preventing Serious Injury and Fatalities Field Guide [C] . Deodete N Ndahondyapo Pitra, Jorge Lima SPE African Health, Safety, Security and Environment and Social Responsibility Conference and Exhibition . 2016

7. Lessons in Modeling, Preventing, and Treating Neural Injury: Improving Bench-to- Bedside Translation. [D] . Turner, Ryan Coddington. 2013

8. Role of Quzhou Fructus Aurantii Extract in Preventing and Treating Acute Lung Injury and Inflammation [O] . Lili Li, Sheng Zhang, Yanfei Xin, -1

9. Poster session 2Morphogenetic mechanisms290MiR-133 regulates retinoic acid pathway during early cardiac chamber specification291Bmp2 regulates atrial differentiation through miR-130 during early heart looping formationDevelopmental genetics294Association of deletion allele of insertion/deletion polymorphism in alpha 2B adrenoceptor gene and hypertension with or without type 2 diabetes mellitus295Association of G1359A polymorphism of the endocannabinoid type 1 receptor (CNR1) with coronary artery disease (CAD) with type 2 diabetes mellitusCell growth, differentiation and stem cells - Vascular298Gamma-secretase inhibitor prevents proliferation and migration of ductus arteriosus smooth muscle cells: a role of Notch signaling in postnatal closure of ductus arteriosus299Mesenchymal stromal-like cells (MLCs) derived from induced pluripotent stem (iPS) cells: a promising therapeutic option to promote neovascularization300Sonic Hedgehog promotes mesenchymal stem cell differentiation to vascular smooth muscle cells in cardiovacsular disease301Proinflammatory cytokine secretion and epigenetic modification in endothelial cells treated LPS-GinfivalisCell death and apoptosis - Vascular304Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipidsTranscriptional control and RNA species - Vascular307MicroRNA-34a role in vascular calcification308Local delivery of a miR-146a inhibitor utilizing a clinically applicable approach attenuates neointima formation after vascular injury309Long noncoding RNA landscape of hypoxic endothelial cells310Specific circulating microRNAs levels associate with hypertension, hyperglycemia and dysfunctional HDL in acute coronary syndrome patientsCytokines and cellular inflammation - Vascular313Phosphodiesterase5A up-regulation in vascular endothelium under pro-inflammatory conditions: a newly disclosed anti-inflammatory activity for the omega-3polyunsaturated aatty acid docosahexaenoic acid314Cardiovascular risk modifying with extra-low dose anticytokine drugs in rhematoid arthritis315Conversion of human M-CSF macrophages into foam cells reduces their proinflammatory responses to classical M1-polarizing activation316Lymphocytic myocarditis coincides with increased plaque inflammation and plaque hemorrhage in coronary arteries, facilitating myocardial infarction317Serum osteoprotegerin level predictsdeclined numerous of circulating endothelial- derived and mononuclear-derived progenitor cells in patients with metabolic syndromeGrowth factors and neurohormones - 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Our experience from a 2-year prospective study in Constanta County, Romania420Epicardial adipose tissue as a predictor of cardiovascular outcome in patients with ACS undergoing PCI?Arterial and pulmonary hypertension423Dependence between heart rhythm disorers and ID polymorphism of ACE gene in hypertensive patients424Molecular mechanisms underlying the beneficial effects of Urocortin 2 in pulmonary arterial hypertension425Inhibition of TGf-b axis and action of renin-angiotensin system in human ascending aorta aneurysms426Early signs of microcirculation and macrocirculation abnormalities in prehypertension427Vascular smooth muscle cell-expressed Tie-2 controls vascular tone428Cardiac and vascular remodelling in the development of chronic thrombo-embolic pulmonary hypertension in a novel swine modelBiomarkers431Arrhythmogenic cardiomyopathy: a new, non invasive biomarker432Can circulating microRNAs distinguish type 1 and type 2 myocardial infarction?433Design of a high-throughput multiplex proteomics assay to identify left ventricular diastolic dysfunction in diabetes434Monocyte-derived and P-selectin-carrying microparticles are differently modified by a low fat diet in patients with cardiovascular risk factors who will and who will not develop a cardiovascular event435Red blood cell distribution width assessment by polychromatic interference microscopy of thin films in chronic heart failure436Invasive and noninvasive evaluation of quality of radiofrequency-induced cardiac denervation in patients with atrial fibrillation437The effect of therapeutic hypothermia on the level of brain derived neurotrophic factor (BDNF) in sera following cardiopulmonary resustitation438Novel biomarkers to predict outcome in patients with heart failure and severe aortic stenosis439Biological factors linking depression and anxiety to cardiovascular disease440Troponins and myoglobin dynamic at coronary arteries graftingInvasive, non-invasive and molecular imaging443Diet composition effects on the genetic typing of the mouse ob mutation: a micro-ultrasound characterization of cardiac function, macro and micro circulation and liver steatosis444Characterization of pig coronary and rabbit aortic lesions using IV-OCT quantitative analysis: correlations with histologyGene therapy and cell therapy447Enhancing the survival and angiogenic potential of mouse atrial mesenchymal cells448VCAM-1 expression in experimental myocardial infarction and its relation to bone marrow-derived mononuclear cell retentionTissue engineering451Advanced multi layered scaffold that increases the maturity of stem cell-derived human cardiomyocytes452Response of engineered heart tissue to simulated ischemia/reperfusion in the presence of acute hyperglycemic conditions453Serum albumin hydrogels prevent de-differentiation of neonatal cardiomyocytes454A novel paintbrush technique for transfer of low viscosity ultraviolet light curable cyan methacrylate on saline immersed in-vitro sheep heart [O] . V Garcia-Martinez, C Lopez Sanchez, W Hamed, 2016

10. Influence of Fiber-Type Composition on Recovery from Tourniquet-Induced Skeletal Muscle Ischemia-Reperfusion Injury. [R] . Walters, T. J., Kragh, J. F., Baer, D. G. 2008

1. Polyethylene glycol rinse solution:An effective way to prevent ischemia-reperfusion injury [J] . Mohamed Amine Zaouali ,Mohamed Bejaoui ,Maria Calvo . 世界胃肠病学杂志：英文版 . 2014,第43期

2. Sodium nitroprusside preventing pulmonary ischemia-reperfusion injury [J] . 许崇武 . 外科研究与新技术 . 2005,第3期

3. Glutamine supplemented parenteral nutrition prevents intestinal ischemia-reperfusion injury in rats [J] . Guo-HaoWu HaoWang Yan-WeiZhang Zhao-HanWu Zhao-GuangWu . 世界胃肠病学杂志：英文版 . 2004,第17期

4. 国内外银杏叶提取物预防心肌缺血再灌注损伤的综述 [C] . 黄志伟 . 全国第十八次银杏学术研讨会 . 2009

5. 抗敏止痒植物组合提取物制备工艺、功效及作用途径研究 [A] . 王领 . 2015