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CELL-CONTROLLED PERFUSION IN CONTINUOUS CULTURE
CELL-CONTROLLED PERFUSION IN CONTINUOUS CULTURE
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机译:连续培养中的细胞控制灌注
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摘要
Methods of protein production in continuous perfusion mammalian cell culture bioreactors are provided. Methods for continuous perfusion culture by allowing cells to self-regulate the rate of addition of perfusion medium to the bioreactor via a pH change are presented. Compositions comprising the perfusion medium as well as the process advantages of using hi-end pH control of perfusion or HIPCOP are also presented.
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