首页> 外国专利> Compositions and methods using same for delivering agents into a target organ protected by a blood barrier

Compositions and methods using same for delivering agents into a target organ protected by a blood barrier

机译:组合物和使用该组合物和方法将药剂递送到受血屏障保护的靶器官中的方法

摘要

A method of delivering a pharmaceutical agent into a target organ protected by a blood barrier is provided. The method comprising administering to a subject in need thereof an amount of liposomes which comprise the pharmaceutical agent, the amount and the liposomes are selected such that the liposomes accumulate in cells of an immune system of the subject to thereby generate liposome loaded immune cells, the liposome loaded immune cells become activated and cross the blood barrier, and an effective amount of the pharmaceutical agent is released from the liposomes in the target organ of the subject.
机译:提供了一种将药剂输送到受血液屏障保护的靶器官中的方法。该方法包括向需要其的受试者施用一定量的包含药物的脂质体,选择该量和脂质体以使脂质体积聚在受试者的免疫系统的细胞中从而产生负载脂质体的免疫细胞。脂质体负载的免疫细胞被激活并穿过血液屏障,并且有效量的药剂从受试者的靶器官中的脂质体释放。

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