首页>
外国专利>
METHOD FOR SUPPRESSING TUMORS BY MIR-200 FAMILY INHIBITION
METHOD FOR SUPPRESSING TUMORS BY MIR-200 FAMILY INHIBITION
展开▼
机译:MIR-200家庭抑制法抑制肿瘤的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Tumor growth was found to be significantly suppressed in vivo by inhibiting both miRNA containing 5′-AACACUG-3′ as a seed sequence and miRNA containing 5′-AAUACUG-3′ as a seed sequence. The inhibition significantly altered the proportion of subpopulations of tumor cells and reduced the tumorigenicity in all subpopulations. The inhibition also exerted a remarkable tumor-shrinking effect on already-formed tumors. The present invention provides novel therapeutic potential against tumor.
展开▼