A method of making an antimicrobial composite article, including the steps: providing a matrix comprising a polymeric material; providing a plurality of second phase particles comprising an antimicrobial agent; melting the matrix to form a matrix me distributing the plurality of second phase particles in the matrix melt at a second phase volume fraction to form a composite me forming a composite article from the composite me and treating the composite article to form an antimicrobial composite article having an exterior surface comprising an exposed portion of the matrix and the plurality of second phase particles. The distributing step can employ an extrusion process. The forming a composite article step can employ an injection molding process. The treating step can employ abrading and plasma-treating the article to define the exterior surface.
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