MOLECULES WITH BIMODAL ACTIVITY DEPLETING TARGET AT LOW DOSE AND INCREASING IMMUNOSUPPRESSION AT HIGHER DOSE

摘要

The present disclosure involves biologically active proteins termed stradobodies and having bimodal activity. Thus, the present disclosure provides compositions and methods providing both target cell destructive and immunosuppressive activities, useful in the treatment of diseases and conditions including autoimmune diseases, inflammatory diseases, infectious diseases, or cancers.