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Method of treating ocular disorders with compounds found in Harderian gland secretions

机译:用哈德氏腺分泌物中发现的化合物治疗眼部疾病的方法

摘要

The present invention is directed to pharmaceutical compositions comprising compounds found in Harderian gland secretions, a method of treating dry eye in a human comprising ophthalmically administering an effective amount of a compound, e.g. a lipid compound, found in Harderian gland secretions, pharmaceutical compositions comprising said lipid compounds, as identified by characteristic chemical data and mass spectra of said lipid compounds, said lipid compound in essentially pure form, and an ophthalmic vehicle comprising a therapeutic agent and a compound present in the secretions of the Harderian gland, e.g. a lipid compound, found in the secretions of the Harderian gland, e.g. a rabbit Harderian gland.
机译:本发明涉及包含在哈德氏腺分泌物中发现的化合物的药物组合物,一种在人中治疗干眼的方法,其包括眼内施用有效量的化合物,例如眼药水。在哈德氏腺分泌物中发现的脂质化合物,药物组合物,其包含通过所述脂质化合物的特征化学数据和质谱鉴定的所述脂质化合物,基本上纯净的形式的所述脂质化合物以及包含治疗剂和化合物的眼科用载体存在于哈德氏腺的分泌物中,例如一种脂类化合物,存在于哈代腺分泌物中,例如兔子哈德良腺。

著录项

  • 公开/公告号US9994511B2

    专利类型

  • 公开/公告日2018-06-12

    原文格式PDF

  • 申请/专利权人 RESTORTEARS LLC;

    申请/专利号US201615051092

  • 发明设计人 DANIEL M. ALBERT;ARTHUR S. POLANS;

    申请日2016-02-23

  • 分类号A61K9;A61K31/22;C07C69/708;A61K45/06;A61K31/225;C07C69/28;C07C69/593;

  • 国家 US

  • 入库时间 2022-08-21 12:55:58

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