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microorganism for methionine production with marked glucose import

机译:葡萄糖进口明显的蛋氨酸生产微生物

摘要

The present invention is related to a recombinant microorganism for improved methionine production comprising modifications to produce methionine from glucose as main carbon source by fermentation, and modifications to improve glucose import, wherein the glucose import is improved by modifying the expression of at least one gene selected from ptsG, sgrT sgrS and dgsA. The invention is also related to a method for the fermentative production of methionine or methionine derivatives comprising the steps of: culturing the recombinant microorganism as described above in an appropriate culture medium comprising a fermentable source of carbon containing glucose and a source of sulphur, and recovering methionine or methionine derivatives from the culture medium.
机译:本发明涉及用于改进蛋氨酸生产的重组微生物,其包括通过发酵从葡萄糖作为主要碳源生产蛋氨酸的修饰和改进葡萄糖输入的修饰,其中通过修饰至少一种选择的基因的表达来改善葡萄糖输入。来自ptsG,sgrT sgrS和dgsA。本发明还涉及用于发酵生产蛋氨酸或蛋氨酸衍生物的方法,该方法包括以下步骤:在包含可发酵碳源的葡萄糖和硫源的适当培养基中培养如上所述的重组微生物,并回收培养基中的蛋氨酸或蛋氨酸衍生物。

著录项

  • 公开/公告号BR112013033675A2

    专利类型

  • 公开/公告日2018-06-19

    原文格式PDF

  • 申请/专利权人 METABOLIC EXPLORER;

    申请/专利号BR20131133675

  • 发明设计人 RTAINER FIGGE;WANDA DISCHERT;

    申请日2012-06-29

  • 分类号C12N9/12;C12P13;C12P13/12;

  • 国家 BR

  • 入库时间 2022-08-21 12:54:04

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