The aqueous nanoemulsu00e3o from essential oil of the leaves of Casearia sylvestris SW. For viral inhibition in herpes simplex type 1

摘要

The aqueous nanoemulsu00e3o from essential oil of the leaves of Casearia sylvestris SW.For viral inhibition in herpes simplex virus type I, the present invention provides nanoemulsion aqueous of the essential oil of the leaves of Casearia sylvestris.With the essential oil rich in sesquiterpenes non oxygenated and has potent antiviral activity to herpes simplex type 1 (HSV - I).This invention allows the incorporation of essential oil insoluble in aqueous medium.The essential oil has in its composition only sesquiterpenes, however, sesquiterpenes non oxygenated which comprise more than 70% of the composition of the essential oil.Studies have found seasonal recurrence of this chemical profile.However, the possibility to solubilize apolar substances in an aqueous medium allows the formulation to be used in the release of insoluble bioactive substances present in the essential oil.With potential antiviral action in the formulations of topical use monocutu00e2neas lesions caused by HSVs - I.Further, the present invention provides information on the profile of the essential oil.The production process of aqueous nanoemulsu00e3o and method for inhibition of viral lesions by topical administration in monocutu00e2neas caused by HSVs - I.