Biodegradable polymeric mats microfibrilares radioesterilizu00e1veis as a system of controlled release of amino acids and vitamins for nutritional supplementation

摘要

Biodegradable polymeric mats microfibrilares radioesterilizu00e1veis as a system of controlled release of amino acids and vitamins for nutritional supplementation.The device MICROFIBRILAR radiesterilizu00e1vel claimed in the report, is for the purpose of controlled release vitaminais B vitamins and essential amino acids.Being worked with the vitamins B2, B5 and B9 and the amino acid L - phenylalanine and L - histidine.The fibers have a target on prisoners of war, patients with severe metabolic disorders and countries with low nutritional index.In the focus on the development of this device were made certain methods, such as the images by scanning electron microscopy.Indicating the presence of fibres in micromu00e9tricas scale; the difratometria of X - ray, which confirmed the interactions crystal and indicated the degree of crystallinity.Being carried out also the DSC through the variation of the enthalpy of fusion, providing data support the determination of the degree of crystallinity of each fiber, and thermal analysis TGA.In the bioactive substances added did not change the temperature of degradation of the polymeric matrix.The results of in vitro tests carried out showed leaching in the polymeric matrix in the hydrolytic degradation.Especially those that contained vitamin B5; the rate of release of the bioactive cargoes of fibres, those retained in most of the loads,As also shown a percentage higher than 95% efficiency of incorporation.Finally, the carpets microfibrilares radioesterilizados with doses of 25 kGy did not have the by-products after gamma radiation.