method for treating, alleviating or protecting (preventing), slowing down or reversing a disease, method for treating, alleviating or protecting (preventing) a disease, use, and, nucleic acid or gene

摘要

alternatively, methods are provided for treating, alleviating or protecting (preventing) congestive heart failure (CHF) or diabetes-related cardiac dysfunction, comprising: providing a nucleic acid, transcription or messenger or gene encoding urocortin 2 and / or urocortin 3 operably linked to a transcriptional regulatory sequence, optionally contained in an expression vehicle or a vector, such as an adeno-associated virus (aav), for example, an aav8 serotype; and administering to an individual or a patient in need thereof, such as a type 2 diabetic (t2dm), for example by iv administration, thereby treating, relieving or protecting against (preventing) t2dm and / or cardiac dysfunction related to diabetes in the individual or patient.