isolated polypeptide, isolated end-coat modified polypeptide, composition of matter, isolated fusion polypeptide, pharmaceutical composition, method of treating an inflammatory disease, use of isolated polypeptide, isolated polynucleotide, nucleic acid structure, and method of determining the potency of one batch of isolated polypeptide

摘要

isolated polypeptide, isolated end-coat modified polypeptide, composition of matter, isolated fusion polypeptide, pharmaceutical composition, method of treating an inflammatory disease, use of isolated polypeptide, isolated polynucleotide, nucleic acid structure, and method of determining the potency of a batch of the isolated polypeptide, provides an isolated polypeptide comprising an amino acid sequence selected from the group consisting of id seq. No. 1-3. Also provided is an isolated end-coat modified polypeptide comprising an amino acid sequence selected from the group consisting of id seq. No. 1-3, characterized in that the modified polypeptide comprises an anti-inflammatory activity. Matter compositions, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease are also provided.