Methods for the production and biossintetizau00e7u00e3o of a compound, the host recombinant product, body biochemical network, construction of nucleic acid or vector of expression, and composition.

摘要

This paper describes biochemical routes to produce acid, 6 - hydroxy - hexanoico using a polypeptide having the activity of beta cetoilase to form a 3 - oxo - 6 - hydroxy - hexanoila COA intermediate.The acid 6 - hydroxy - hexanoico can be converted to form enzyme for adipic acid, caprolactam, hexamethylene diamine acid, 6 - aminohexanoico, or 1.6 hexanodiol.This document also describes recombinant hosts which produce acid, 6 - hydroxy - hexanoico and adipic acid, caprolactam, hexamethylene diamine and acid, 6 - aminohexanoico, 1.6 hexanodiol.