methods for deriving a gene signature biomarker and for treating a patient having a tumor, method and system for testing a tumor sample removed from a patient, and kit.

摘要

It is a gene expression platform that is a combination of a set of genes that are correlated to the response to a pd-1 antagonist in multiple tumor types and a set of normalization genes. A method and system for using the gene expression platform to derive antitumor response gene signature biomarkers from a pd-1 antagonist and to test patient samples for predictive gene signature biomarkers are also disclosed.