? antibody, pharmaceutical composition, isolated polynucleotide molecule, vector, cell, and method for preventing, treating or ameliorating at least one influenza infection symptom?

摘要

The present invention provides monoclonal antibodies, or antigen binding fragments thereof, that bind to influenza hemagglutinin (ha) protein, pharmaceutical compositions comprising the antibodies and methods of use. The antibodies of the invention are useful for inhibiting or neutralizing influenza virus activity, thereby providing means for treating or preventing influenza infection in humans. In some embodiments, the invention provides for the use of one or more antibodies that bind to influenza ha to prevent viral attachment and / or viral entry into host cells. The antibodies of the invention may be used prophylactically or therapeutically and may be used alone or in combination with one or more other antiviral agents or vaccines.