antibody, methods for reducing and increasing the binding affinity of a human cd3 binding antibody, for treating and diagnosing a disease, for producing an antibody, and for detecting the presence of cd3 antigen, nucleic acid construct, expression vector, host cell, composition, and kit?

摘要

The present invention relates to humanized or chimeric cd3-binding antibodies. furthermore it relates to bispecific antibodies, compositions, pharmaceutical compositions, use of said antibodies in the treatment of a disease, and method of treatment.