TOPIC FORMULATIONS UNDERSTANDING A 1-N-ARYLPIRAZOL DERIVATIVE AND A FORMAMIDINE

摘要

"topical formulations comprising a 1-n-arylpyrazole derivative and a formamidine". The present invention provides, among other things, novel topical formulations comprising at least one 1-n-arylpyrazole derivative and a formamidine, such as amitraz, and methods for treating, controlling or preventing parasite infestations in mammals or birds. The formulations of the invention include formulations for spot application, spreading or spraying and may include an additional ectoparasiticide such as an igr compound, an avermectin or milbemycin derivative, or a pyrethroid insecticide, and / or anthelmintics such as benzimidazoles or imidazothiazoles. . The formulation of the invention provides a longer duration of parasite control at a faster rate of control. The formula of the invention remains effective for up to three months after the first application. In addition, the formulations of the invention prevent the attachment of ticks to the animal, thereby providing protection against tick-borne diseases. Ectoparasites that can be controlled, treated or prevented by the present invention include ticks, fleas, mites, scabies, lice, mosquitoes, flies and insect larvae in cattle.