And NTPDases recombinants, use in the production of diagnostic kit for detection of antibodies in leishmanioses caused by species of the genus Leishmania

摘要

And NTPDases recombinants, use in the production of diagnostic kit for detection of antibodies in leishmanioses caused by species of the genus Leishmania.This invention relates to protein family and NTPDases recombinants that can be used as antigens in diagnostic kits of leishmanioses animals and human.The proteins of the family of E - NTPDases recombinants obtained may be employed in the production of diagnostic kits for the detection of antibodies in leishmanioses,Using tests of the type immunological.These tests can be applied in the detection of seropositive individuals in control programs leishmanioses or in the laboratory diagnosis of leishmanioses.These proteins may also be used in forecasting and vaccine trials.In the rational design of chemotherapeutic agents for the treatment of leishmanioses and development of monoclonal antibodies to be used in the diagnosis, prognosis or therapy of leishmanioses.