A hybrid transmission method including a microbial strain for a fermentation medium includes the following steps:(i) A propylene organism adapted to Clostridium sp is provided, which is combined with the functional metabolic pathway of wood ljungdahl;(II) metabolism of a carbon source with the use of an organism; raw materials include Co, CO2, carbonate, carbonate, carbonate, H2, glycerin, methanol, formate, urea or a combination thereof; and(iii) cultivating the organism in a fermentation medium, and a fermentation broth is formed with a bioproduct, where the bioproduct is organic acid, such as acetic acid.Alternatively, the method includes a stage in which biological products can be isolated from the culture medium.
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