SALES Y FORMAS SOLIDAS DEL ACIDO 1-(((Z)-(1-(2-AMINOTIAZOL-4-IL)-2-OXO-2-(((3S,4R)-2-OXO-4-((2-OXOOXAZOLIDIN-3-IL)METIL)-1-SULFOAZETIDIN-3-IL)AMINO)ETILIDENO)AMINO)OXI)CICLOPROPANOCARBOXILICO; METODOS DE PREPARACION; FORMAS CRISTALINAS; COMPOSICION FARMACEUTICA; USO EN EL TRATAMIENTO DE UNA INFECCION BACTERIANA GRAM NEGATIVA.

摘要

The invention provides new solid forms, salts and polymorphs of 1-(((Z)-(1-(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3-yl)amino)ethylidene)amino)oxy)cyclopropanecarboxylic acid (referred to herein as Compound X), pharmaceutical compositions containing them, and processes for their manufacture and use in therapy.