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A method for Testing the response ex vivo Cell populations of stem cells to a drug or combination of drugs

机译:一种测试干细胞对药物或药物组合的离体反应的方法

摘要

The Invention relates to a method for producing an artificial Environment of primary Cell populations.Particularly a tumor Environment artificial populations of primary tumor cells and their use in a method ex vivo to assess the cellular response of primary tumor Cell PopulationsAs to a drug or drugs.The Method of the invention comprises the incubation of tumor cells in the primary tumor and the artificial Environment of the drug or drugs and analyze the response of Populations cÉluThe primary tumor.The incubation of primary tumor cells in tumor Environment, artificialThe viability of the tumor cells and / or induces higher levels of proliferation of tumor cells and, accordingly,Increases the sensitivity and accuracy of the test with regard to the Drugs tested.
机译:本发明涉及产生原代细胞群的人工环境的方法。特别是原代肿瘤细胞的肿瘤环境人工群及其在离体方法中用于评估原代肿瘤细胞群A对一种或多种药物的细胞应答的用途。本发明的方法包括在原发肿瘤中孵育肿瘤细胞和一种或多种药物的人工环境,并分析种群对原发肿瘤的反应。在肿瘤环境中人工孵育原发性肿瘤细胞,肿瘤细胞的生存力和/或诱导更高水平的肿瘤细胞增殖,并因此提高了测试药物对测试药物的敏感性和准确性。

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