Biparatópicos polypeptides that antagonize WNT signaling in tumor cells

摘要

The Invention provides polipÉptidos Union Cross reaction with novel biparatÓpicos LRP5 / 6 and, in particular,Single immunoglobulin variable Domain constructs of Cross reaction with LRP5 / 6 biparatÓpicos novel Routes to inhibit WNT signaling.The Invention also relates to specific sequences of these polipÉptidos, Methods for Preparation and Methods for use, including methods for the treatment of diseases,Such as cancer.