Conjugation of Pisces antigen structure to mexotelin and CD3

摘要

Generally speaking, the invention refers to a bisexual antibody, including the first binding domain connecting human msln on the target cell surface and the second binding domain connecting human CD3 on the T cell surface. The invention provides a polynucleotide encoded for antibody construction, a vector including polynucleotide and a host cell transformed or transformed by such polynucleotide or vector. In addition, the invention provides a procedure for the production of the antibody,This is an antibody building for medical use and a package that includes such antibody buildings.