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Rnip and its application in the method and composition of inhibiting nrarp gene expression

机译:Rnip及其在抑制nrarp基因表达的方法和组成中的应用

摘要

The invention refers to the rnip molecule and its use in pharmaceutical methods and synthesis to inhibit the expression of nrarp gene. The invention also refers to the use of this RNAP molecule in the treatment and / or prevention of new vascular diseases or disorders related to the increase of nrarp gene expression and / or activity. This eye condition was selected from the age-related macular degeneration (AMD) group.Ischemic retinopathy, diabetic crystalline edemaDiffuse diabetic retinopathy (PDR)Diabetic retinitis (DRI)Diabetic retinoedema (DRE) and retinopathy prematurity (ROP) and their combinations.
机译:本发明涉及rnip分子及其在抑制nrarp基因表达的药物方法和合成中的用途。本发明还涉及该RNAP分子在治疗和/或预防与nrarp基因表达和/或活性增加有关的新的血管疾病或病症中的用途。该眼病选自年龄相关性黄斑变性(AMD)组,缺血性视网膜病,糖尿病性晶体水肿,弥漫性糖尿病性视网膜病(PDR),糖尿病性视网膜炎(DRI),糖尿病性视网膜水肿(DRE)和视网膜病的早产(ROP)及其组合。

著录项

  • 公开/公告号CO2018003596A2

    专利类型

  • 公开/公告日2018-08-31

    原文格式PDF

  • 申请/专利权人 SYLENTIS SAU;

    申请/专利号CO20180003596

  • 申请日2018-04-04

  • 分类号C12N15/113;A61K31/713;A61P9/10;A61P27/02;C07H21/02;

  • 国家 CO

  • 入库时间 2022-08-21 12:53:08

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